FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RIP3
反应性
Human
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
57kD
MW(Observed)
57kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1371R
特异性
Endogenous
基因名称
RIPK3 RIP3
蛋白名称
Receptor-interacting serine/threonine-protein kinase 3 (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
别名
Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;
Organism-1
Human
基因ID-1
11035
SwissProt-1
Q9Y572
Organism-2
Mouse
SwissProt-2
Q9QZL0
Organism-3
Rat
基因ID-3
246240
SwissProt-3
Q9Z2P5
背景
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. .
