FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FoxP2
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
80kD
MW(Observed)
95kD
推荐稀释比
WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1405R
特异性
Endogenous
基因名称
FOXP2
蛋白名称
Forkhead box protein P2
别名
FOXP2;CAGH44;TNRC10;Forkhead box protein P2;CAG repeat protein 44;Trinucleotide repeat-containing gene 10 protein
Organism-1
Human
基因ID-1
93986
SwissProt-1
O15409
Organism-2
Mouse
SwissProt-2
P58463
背景
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isofor
细胞定位
Nucleus .
