Raptor (Phospho Ser792) Rabbit mAb

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¥880.00

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产品规格:
  • 50μL
货号:

FAB2622232

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商品描述
  • 靶点-Target

    Raptor

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    149kD

  • MW(Observed)

    150kD

  • 推荐稀释比

    WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    Monoclonal

  • 免疫原

    PT1403R

  • 特异性

    Raptor (Phospho Ser792) antibody detects endogenous levels of Human Mouse Rat Raptor (phospho-Ser792).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsYS

  • 基因名称

    RPTOR KIAA1303 RAPTOR

  • 蛋白名称

    Raptor (Ser792)

  • 别名

    Regulatory-associated protein of mTOR;Raptor;p150 target of rapamycin;TOR;-scaffold protein;

  • Organism-1

    Human

  • 基因ID-1

    57521

  • SwissProt-1

    Q8N122

  • Organism-2

    Mouse

  • SwissProt-2

    Q8K4Q0

  • 背景

    This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

  • 细胞定位

    Cytoplasm. Lysosome. Cytoplasmic granule . Targeting to lysosomes depends on amino acid availability. In arsenite-stressed cells, accumulates in stress granules when associated with SPAG5 and association with lysosomes is drastically decreased.