Tuberin (Phospho Thr1462) Rabbit mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2622219
- 产品信息
商品描述
靶点-Target
Tuberin
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Phospho
MW(Calculated)
201kD
MW(Observed)
201kD
推荐稀释比
IHC 1:100-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1415R
特异性
Tuberin (Phospho Thr1462) Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GYtIS
基因名称
TSC2 TSC4
蛋白名称
Tuberin
别名
TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein
Organism-1
Human
基因ID-1
7249
SwissProt-1
P49815
Organism-2
Mouse
SwissProt-2
Q61037
Organism-3
Rat
基因ID-3
24855
SwissProt-3
P49816
背景
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.





