Tuberin (Phospho Thr1462) Rabbit mAb

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¥880.00

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产品规格:
  • 50μL
货号:

FAB2622219

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商品描述
  • 靶点-Target

    Tuberin

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    201kD

  • MW(Observed)

    201kD

  • 推荐稀释比

    IHC 1:100-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    Monoclonal

  • 免疫原

    PT1415R

  • 特异性

    Tuberin (Phospho Thr1462) Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GYtIS

  • 基因名称

    TSC2 TSC4

  • 蛋白名称

    Tuberin

  • 别名

    TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein

  • Organism-1

    Human

  • 基因ID-1

    7249

  • SwissProt-1

    P49815

  • Organism-2

    Mouse

  • SwissProt-2

    Q61037

  • Organism-3

    Rat

  • 基因ID-3

    24855

  • SwissProt-3

    P49816

  • 背景

    Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.