- 产品信息
商品描述
靶点-Target
CHAT
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
83kD
MW(Observed)
83kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1411R
特异性
Endogenous
基因名称
CHAT
蛋白名称
Choline O-acetyltransferase
别名
CHAT;Choline O-acetyltransferase;CHOACTase;ChAT;Choline acetylase
Organism-1
Human
基因ID-1
1103
SwissProt-1
P28329
Organism-2
Mouse
SwissProt-2
Q03059
Organism-3
Rat
SwissProt-3
P32738
背景
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],
细胞定位
nucleus,cytoplasm,cytosol,presynapse,





