FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-1β
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
Mouse IgG1/Kappa
修饰-Modification
Unmodified
MW(Calculated)
31kD
MW(Observed)
35kD,31kD,20kD
推荐稀释比
IHC 1:200-1000;WB 1:2000-1:10000;IF 1:100-500;ELISA 1:1000-5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PTR1433
特异性
Endogenous
基因名称
IL1B IL1F2
蛋白名称
Interleukin-1 beta (IL-1 beta) (Catabolin)
别名
IL1B;IL1F2;Interleukin-1 beta;IL-1 beta;Catabolin
Organism-1
Human
基因ID-1
3553
SwissProt-1
P01584
Organism-2
Mouse
基因ID-2
16176
SwissProt-2
P10749
Organism-3
Rat
SwissProt-3
Q63264
背景
interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],
细胞定位
Secreted
