- 产品信息
商品描述
靶点-Target
MCAD
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
47kD
MW(Observed)
45kD
推荐稀释比
IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1435R
特异性
Endogenous
基因名称
ACADM
蛋白名称
Medium-chain specific acyl-CoA dehydrogenase mitochondrial
别名
ACADM;Medium-chain specific acyl-CoA dehydrogenase, mitochondrial;MCAD
Organism-1
Human
基因ID-1
34
SwissProt-1
P11310
Organism-2
Mouse
基因ID-2
11364
SwissProt-2
P45952
Organism-3
Rat
基因ID-3
24158
SwissProt-3
P08503
背景
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .





