FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TXNRD1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
67kD
MW(Observed)
60kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1432R
特异性
Endogenous
基因名称
TXNRD1 GRIM12 KDRF
蛋白名称
Thioredoxin reductase 1, cytoplasmic (TR) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Thioredoxin reductase TR1)
Organism-1
Human
基因ID-1
7296
SwissProt-1
Q16881
Organism-2
Mouse
SwissProt-2
Q9JMH6
Organism-3
Rat
SwissProt-3
O89049
背景
thioredoxin reductase 1(TXNRD1) Homo sapiens This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus .; [Isoform 5]: Cytoplasm .
