- 产品信息
商品描述
靶点-Target
Cytokeratin 1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
66kD
MW(Observed)
66kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1421R
特异性
Endogenous
基因名称
KRT1 KRTA
蛋白名称
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
别名
67 kDa cytokeRatin;CK-1;CK1;CytokeRatin-1;CytokeRatin1;EHK;EHK1;Epidermolytic hyperkeRatosis 1;EPPK;Hair alpha protein;K1;K2C1_HUMAN;KeRatin;KeRatin type II cytoskeletal 1;KeRatin-1;KeRatin1;KRT 1;Krt1;KRT1A;NEPPK;type II cytoskeletal 1;Type II keRatin Kb1;Type-II keRatin Kb1
Organism-1
Human
基因ID-1
3848
SwissProt-1
P04264
背景
keratin 1(KRT1) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic, Membranous





