- 产品信息
商品描述
靶点-Target
eEF2K
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
85kD
MW(Observed)
105kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1420R
特异性
Endogenous
基因名称
EEF2K
蛋白名称
Eukaryotic elongation factor 2 kinase
别名
EEF2K;Eukaryotic elongation factor 2 kinase;eEF-2 kinase;eEF-2K;Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Organism-1
Human
基因ID-1
29904
SwissProt-1
O00418
Organism-2
Mouse
基因ID-2
13631
SwissProt-2
O08796
Organism-3
Rat
基因ID-3
25435
SwissProt-3
P70531
背景
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],
细胞定位
cytoplasm,cytosol,postsynaptic density,





