FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CCR7
反应性
Human
应用
FC,IF
宿主物种-Host Species
Mouse
同种型-Isotype
Mouse IgG1/Kappa
修饰-Modification
Unmodified
推荐稀释比
IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
纯化工艺
Protein A
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
克隆号
Monoclonal
免疫原
PTF0059
特异性
Endogenous
基因名称
CCR7
蛋白名称
C-C chemokine receptor type 7
别名
CCR7;CMKBR7;EBI1;EVI1;C-C chemokine receptor type 7;C-C CKR-7;CC-CKR-7;CCR-7;BLR2;CDw197;Epstein-Barr virus-induced G-protein coupled receptor 1;EBI1;EBV-induced G-protein coupled receptor 1;MIP-3 beta receptor;CD antigen CD19
Organism-1
Human
基因ID-1
1236
SwissProt-1
P32248
背景
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014],
细胞定位
Cell membrane; Multi-pass membrane protein.
