FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IgM
反应性
Human
应用
FC,IF,WB
宿主物种-Host Species
Mouse
同种型-Isotype
Mouse IgG1/Kappa
修饰-Modification
Unmodified
MW(Calculated)
50kD
MW(Observed)
80kD
推荐稀释比
WB 1:4000-1:20000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
纯化工艺
Protein A
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
克隆号
Monoclonal
免疫原
PTF0046
特异性
Endogenous
基因名称
igm
别名
AGM1;Constant region of heavy chain of IgM;DKFZp686I15196;DKFZp686I15212;FLJ00385;Ig mu chain C region;IGHM;Immunoglobin heavy constant mu;Immunoglobulin mu;MGC104996;MGC52291;MU;VH.
Organism-1
Human
基因ID-1
3507
SwissProt-1
P01871
Organism-2
Mouse
SwissProt-2
P01872
背景
Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which d
细胞定位
[Isoform 1]: Secreted. During differentiation, B-lymphocytes switch from expression of membrane-bound IgM to secretion of IgM.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.
