FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD1c
反应性
Human
应用
FC,IF
宿主物种-Host Species
Mouse
同种型-Isotype
Mouse IgG1/Kappa
修饰-Modification
Unmodified
推荐稀释比
IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
纯化工艺
Protein A
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
克隆号
Monoclonal
免疫原
PTF0039
特异性
Endogenous
基因名称
CD1C
蛋白名称
T-cell surface glycoprotein CD1c
别名
CD1C;T-cell surface glycoprotein CD1c;CD1c
Organism-1
Human
基因ID-1
911
SwissProt-1
P29017
背景
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein. Lysosome . Subject to intracellular trafficking between the cell membrane and endosomes. .
