- 产品信息
商品描述
靶点-Target
IL-7R
反应性
Human
应用
FC,IF,WB
宿主物种-Host Species
Mouse
同种型-Isotype
Mouse IgG1/Kappa
修饰-Modification
Unmodified
MW(Calculated)
52kD
MW(Observed)
70kD
推荐稀释比
WB 1:4000-1:20000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
纯化工艺
Protein A
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
克隆号
Monoclonal
免疫原
PTF0044
特异性
Endogenous
基因名称
IL7R
蛋白名称
Interleukin-7 receptor subunit alpha
别名
IL7R;Interleukin-7 receptor subunit alpha;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CDw127;CD antigen CD127
Organism-1
Human
基因ID-1
3575
SwissProt-1
P16871
背景
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015],
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Secreted.





