NF-M (Phospho Ser614/Ser619) Rabbit mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2622154
- 产品信息
商品描述
靶点-Target
NF-M
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Phospho
MW(Calculated)
103kD
MW(Observed)
180kD
推荐稀释比
IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1444R
特异性
NF-M (Phospho Ser614/Ser619) Antibody detects endogenous levels of NF-M protein only when phosphorylated at S614/S619.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):KAkSP/VPkSP
基因名称
NEFM
蛋白名称
Neurofilament medium polypeptide
别名
NEFM;NEF3;NFM;Neurofilament medium polypeptide;NF-M;160 kDa neurofilament protein;Neurofilament 3;Neurofilament triplet M protein
Organism-1
Human
基因ID-1
4741
SwissProt-1
P07197
Organism-2
Mouse
SwissProt-2
P08553
背景
neurofilament, medium polypeptide(NEFM) Homo sapiens Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon .





