FGF-2 Polyclonal Antibody
¥680.00
IKK-α/β (Phospho Ser176/180) Rabbit mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2622146
- 产品信息
商品描述
靶点-Target
IKKα/β
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Phospho
MW(Calculated)
85kD,87kD
MW(Observed)
80kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT0746R
特异性
IKK-α/β (Phospho Ser176/180) antibody detects endogenous levels of IKKα/β only when phosphorylated at S176/S180.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QGsLC/CTsFV
基因名称
CHUK/IKBKB
蛋白名称
Inhibitor of nuclear factor kappa-B kinase subunit alpha
别名
CHUK;IKKA;TCF16;Inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase alpha;IKK-A;IKK-alpha;IkBKA;IkappaB kinase;Conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;IKK1;Nuclear factor NF-kappa-B
Organism-1
Human
基因ID-1
1147;3551
SwissProt-1
O15111;O14920
Organism-2
Mouse
基因ID-2
16150
Organism-3
Rat
基因ID-3
84351
SwissProt-3
Q9QY78
背景
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus.
