- 产品信息
商品描述
靶点-Target
PRLR
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
70kD
MW(Observed)
95kD
推荐稀释比
IHC 1:200-1:500;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1312R
特异性
Endogenous
基因名称
PRLR
蛋白名称
Prolactin receptor
别名
PRL-R
Organism-1
Human
基因ID-1
5618
SwissProt-1
P16471
Organism-2
Mouse
SwissProt-2
Q08501
Organism-3
Rat
SwissProt-3
P05710
背景
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011],
细胞定位
Membrane ; Single-pass type I membrane protein .; [Isoform 7]: Secreted.





