- 产品信息
商品描述
靶点-Target
SLC11A2
反应性
Human
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
62kD
MW(Observed)
80-100kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1401R
特异性
Endogenous
基因名称
SLC11A2 DCT1 DMT1 NRAMP2 OK/SW-cl.20
蛋白名称
Natural resistance-associated macrophage protein 2
别名
Natural resistance-associated macrophage protein 2;NRAMP 2;Divalent cation transporter 1;Divalent metal transporter 1;DMT-1;
Organism-1
Human
基因ID-1
4891
SwissProt-1
P49281
Organism-2
Mouse
基因ID-2
18174
SwissProt-2
P49282
Organism-3
Rat
基因ID-3
25715
SwissProt-3
O54902
背景
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010],
细胞定位
[Isoform 2]: Cell membrane ; Multi-pass membrane protein . Early endosome .; Endosome membrane ; Multi-pass membrane protein . Mitochondrion outer membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Also found in extracellular vesicles different from exosomes. .





