FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CCR2
反应性
Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
42kD
MW(Observed)
43kD
推荐稀释比
WB 1:1000-1:20000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1511R
特异性
Endogenous
基因名称
CCR2
蛋白名称
C-C chemokine receptor type 2
别名
CCR2;CMKBR2;C-C chemokine receptor type 2;C-C CKR-2;CC-CKR-2;CCR-2;CCR2;Monocyte chemoattractant protein 1 receptor;MCP-1-R;CD192
Organism-1
Human
基因ID-1
729230
SwissProt-1
P41597
Organism-2
Mouse
基因ID-2
12772
SwissProt-2
P51683
Organism-3
Rat
基因ID-3
60463
SwissProt-3
O55193
背景
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009],
细胞定位
Cell membrane ; Multi-pass membrane protein . The chemoattractant receptors are distributed throughout the cell surface; after stimulation with a ligand, such as CCL2, they are rapidly recruited into microdomain clusters at the cell membrane. .
