- 产品信息
商品描述
靶点-Target
MerTK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
修饰-Modification
Unmodified
MW(Calculated)
110kD
MW(Observed)
180kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
Monoclonal
免疫原
PT1519R
特异性
Endogenous
基因名称
MERTK
蛋白名称
Tyrosine-protein kinase Mer
别名
MERTK;MER;Tyrosine-protein kinase Mer;Proto-oncogene c-Mer;Receptor tyrosine kinase MerTK
Organism-1
Human
基因ID-1
10461
SwissProt-1
Q12866
Organism-2
Mouse
SwissProt-2
Q60805
背景
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





