- 产品信息
商品描述
靶点-Target
VGLU1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
62kD
MW(Observed)
62kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1164R
特异性
Endogenous
基因名称
SLC17A7 BNPI VGLUT1
蛋白名称
VGLU1
别名
Vesicular glutamate transporter 1;VGluT1;Brain-specific Na;+;-dependent inorganic phosphate cotransporter;Solute carrier family 17 member 7;
Organism-1
Human
基因ID-1
57030
SwissProt-1
Q9P2U7
Organism-2
Mouse
基因ID-2
72961
SwissProt-2
Q3TXX4
Organism-3
Rat
基因ID-3
116638
SwissProt-3
Q62634
背景
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008],
细胞定位
Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.,





