- 产品信息
商品描述
靶点-Target
ACSS2
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
79kD
MW(Observed)
79kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1204R
特异性
Endogenous
基因名称
ACSS2 ACAS2
蛋白名称
Acetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)
Organism-1
Human
基因ID-1
55902
SwissProt-1
Q9NR19
Organism-2
Mouse
基因ID-2
60525
SwissProt-2
Q9QXG4
背景
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
细胞定位
Catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,Function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,





