- 产品信息
商品描述
靶点-Target
CXCR-7
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
41kD
MW(Observed)
42kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1221R
特异性
Endogenous
基因名称
CXCR7
蛋白名称
C-X-C chemokine receptor type 7
别名
CXCR7;CMKOR1;GPR159;RDC1;C-X-C chemokine receptor type 7;CXC-R7;CXCR-7;Chemokine orphan receptor 1;G-protein coupled receptor 159;G-protein coupled receptor RDC1 homolog;RDC-1
Organism-1
Human
基因ID-1
57007
SwissProt-1
P25106
Organism-2
Mouse
基因ID-2
12778
SwissProt-2
P56485
Organism-3
Rat
基因ID-3
84348
SwissProt-3
O89039
背景
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008],
细胞定位
Caution:Was originally (PubMed:1675791) thought to be the receptor for VIP.,Function:Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells.,





