- 产品信息
商品描述
靶点-Target
Dkk-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
29kD
MW(Observed)
28-40kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1237R
特异性
Endogenous
基因名称
DKK1
蛋白名称
Dickkopf-related protein 1
别名
DKK1;Dickkopf-related protein 1;Dickkopf-1;Dkk-1;hDkk-1;SK
Organism-1
Human
基因ID-1
22943
SwissProt-1
O94907
Organism-2
Mouse
基因ID-2
13380
SwissProt-2
O54908
背景
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
细胞定位
Function:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta.,





