FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
YY1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
45kD
MW(Observed)
65kD
推荐稀释比
IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1231R
特异性
Endogenous
基因名称
YY1 INO80S
蛋白名称
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
别名
TYY1;Transcriptional repressor protein YY1;Delta transcription factor;INO80 complex subunit S;NF-E1;Yin and yang 1;YY-1;
Organism-1
Human
基因ID-1
7528
SwissProt-1
P25490
Organism-2
Mouse
基因ID-2
22632
SwissProt-2
Q00899
背景
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008],
细胞定位
Function:Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. May play an important role in development and differentiation. The function of YY1 as an activator or a repressor is specified by the presence of other proteins. For example it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associated with the nuclear matrix.,subunit:Interacts with YAF2 through the region encompassing the first and second zinc fingers. Interacts with INO80.,
