FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RHEB
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
21kD
MW(Observed)
21kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1285R
特异性
Endogenous
基因名称
RHEB RHEB2
蛋白名称
RHEB
别名
Ras homolog enriched in brain
Organism-1
Human
基因ID-1
6009
SwissProt-1
Q15382
Organism-2
Mouse
基因ID-2
19744
SwissProt-2
Q921J2
Organism-3
Rat
SwissProt-3
Q62639
背景
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008],
细胞定位
Function:Not known; binds GTP and exhibits intrinsic GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rheb family.,tissue specificity:Ubiquitous. Highest levels observed in skeletal and cardiac muscle.,
