FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Flotillin-2
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
47kD
MW(Observed)
47kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1253R
特异性
Endogenous
基因名称
FLOT2 ESA1 M17S1
蛋白名称
Flotillin-2
别名
FLOT2;ESA1;M17S1;Flotillin-2;Epidermal surface antigen;ESA;Membrane component chromosome 17 surface marker 1
Organism-1
Human
基因ID-1
2319
SwissProt-1
Q14254
Organism-2
Mouse
基因ID-2
14252
SwissProt-2
Q60634
Organism-3
Rat
基因ID-3
83764
SwissProt-3
Q9Z2S9
背景
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008],
细胞定位
Function:May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.,similarity:Belongs to the band 7/mec-2 family. Flotillin subfamily.,subcellular location:Membrane-associated protein of caveolae.,subunit:Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2.,tissue specificity:In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.,
