FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Angiopoietin 1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
58kD
MW(Observed)
58kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1259R
特异性
Endogenous
基因名称
ANGPT1
蛋白名称
Angiopoietin-1
别名
ANGPT1;KIAA0003;Angiopoietin-1;ANG-1
Organism-1
Human
基因ID-1
284
SwissProt-1
Q15389
Organism-2
Mouse
SwissProt-2
O08538
背景
function:Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.,miscellaneous:It may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart.,online information:Angiopoietin entry,PTM:Glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,
细胞定位
angiogenesis, ovarian follicle development, blood vessel development, response to hypoxia, vasculature development,reproductive developmental process, protein complex assembly, cell surface receptor linked signal transduction,enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, sex differentiation, response to nutrient, gonad development, female gonad development, response to endogenous stimulus, response to hormone stimulus, response to extracellular stimulus, response to organic substance, ovulation cycle process, regeneration, organ regeneration, response to nutrient levels, multicellular organism reproduction, response to vitamin, response to vitamin B3, ovulation cycle, response to estrogen stimulus,macromolecular complex subunit organization, development of primary sexual characteristics, regulation of anti-apoptosis, positive regulation of anti-apoptosis, development of primary female sexual characteristics, female sex differentiation, rhythmic process, blood vessel morphogenesis, response to steroid hormone stimulus, reproductive structure development, reproductive process in a multicellular organism, protein oligomerization, protein homooligomerization, macromolecular complex assembly, protein complex biogenesis, response to oxygen levels,
