FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HMGCR
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
98kD
MW(Observed)
98kD
推荐稀释比
IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1309R
特异性
Endogenous
基因名称
HMGCR
蛋白名称
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)
Organism-1
Human
基因ID-1
3156
SwissProt-1
P04035
Organism-2
Mouse
基因ID-2
15357
SwissProt-2
Q01237
Organism-3
Rat
基因ID-3
25675
SwissProt-3
P51639
细胞定位
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis . HMGCR is the main target of statins, a class of cholesterol-lowering drugs .
