- 产品信息
商品描述
靶点-Target
NK-1R
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
46kD
MW(Observed)
46kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1302R
特异性
Endogenous
基因名称
TACR1
蛋白名称
Substance-P receptor
别名
TACR1;NK1R;TAC1R;Substance-P receptor;SPR;NK-1 receptor;NK-1R;Tachykinin receptor 1
Organism-1
Human
基因ID-1
6869
SwissProt-1
P25103
Organism-2
Mouse
基因ID-2
21336
SwissProt-2
P30548
Organism-3
Rat
基因ID-3
24807
SwissProt-3
P14600
背景
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008],
细胞定位
Function:This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.,online information:Tachykinin entry,similarity:Belongs to the G-protein coupled receptor 1 family.,





