- 产品信息
商品描述
靶点-Target
TROP-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
36kD
MW(Observed)
45-65kD
推荐稀释比
IHC 1:200-1:1000;WB 1:10000-1:50000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1308R
特异性
Endogenous
基因名称
TACSTD2
蛋白名称
Tumor-associated calcium signal transducer 2
别名
TACSTD2;GA733-1;M1S1;TROP2;Tumor-associated calcium signal transducer 2;Cell surface glycoprotein Trop-2;Membrane component chromosome 1 surface marker 1;Pancreatic carcinoma marker protein GA733-1
Organism-1
Human
基因ID-1
4070
SwissProt-1
P09758
Organism-2
Mouse
基因ID-2
56753
SwissProt-2
Q8BGV3
Organism-3
Rat
基因ID-3
494343
SwissProt-3
Q6P9Z6
背景
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009],
细胞定位
Disease:Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.,Function:GA733 tumor-associated antigen gene family may function as growth factor receptors.,PTM:The N-terminus is blocked.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Placenta, pancreatic carcinoma cell lines.,





