FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Smo
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
86kD
MW(Observed)
100kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1379R
特异性
Endogenous
基因名称
SMO
蛋白名称
Smoothened homolog
别名
SMO;SMOH;Smoothened homolog;SMO;Protein Gx
Organism-1
Human
基因ID-1
6608
SwissProt-1
Q99835
Organism-2
Mouse
基因ID-2
319757
SwissProt-2
P56726
Organism-3
Rat
基因ID-3
25273
SwissProt-3
P97698
背景
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010],
细胞定位
Disease:Defects in SMO are involved in basal cell carcinoma (BCC).,Function:G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO).,similarity:Belongs to the G-protein coupled receptor Fz/Smo family.,similarity:Contains 1 FZ (frizzled) domain.,
