FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NCSTN
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
MW(Calculated)
78kD
MW(Observed)
110-120kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1284R
特异性
Endogenous
基因名称
NCSTN KIAA0253 UNQ1874/PRO4317
蛋白名称
Nicastrin
Organism-1
Human
基因ID-1
23385
SwissProt-1
Q92542
Organism-2
Mouse
基因ID-2
59287
SwissProt-2
P57716
Organism-3
Rat
基因ID-3
289231
SwissProt-3
Q8CGU6
细胞定位
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) . The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
