FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AurC
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
36kD
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1145R
特异性
Endogenous
基因名称
AURKC
蛋白名称
Serine/threonine-protein kinase 13/Aurora kinase C
别名
AIE2;AIK3;AIRK3;ARK3;STK13;Aurora kinase C;Aurora 3;Aurora/IPL1 related kinase 3;ARK 3;Aurora related kinase 3;Serine/threonine protein kinase 13;Aurora/IPL1related kinase 3;Aurorarelated kinase 3;Serine/threonineprotein kinase 13;Serine/threonineprotein kinase auroraC;
Organism-1
Human
基因ID-1
6795
SwissProt-1
Q9UQB9
背景
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
细胞定位
Nucleus,Chromosome,Chromosome, centromere,Cytoplasm, cytoskeleton, spindle,Note: Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remains in the midbody during cytokinesis.
