FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PGK1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
45kD
MW(Observed)
45kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1141R
特异性
Endogenous
基因名称
PGK1 PGKA MIG10 OK/SW-cl.110
蛋白名称
Phosphoglycerate kinase 1 (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
别名
Phosphoglycerate kinase 1;Cell migration-inducing gene 10 protein;Primer recognition protein 2;PRP 2;
Organism-1
Human
基因ID-1
5230
SwissProt-1
P00558
Organism-2
Mouse
基因ID-2
18655
SwissProt-2
P09411
Organism-3
Rat
基因ID-3
24644
SwissProt-3
P16617
背景
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
细胞定位
Cytoplasm.
