FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Integrin αV
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
116kD
MW(Observed)
116kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1136R
特异性
Endogenous
基因名称
ITGAV MSK8 VNRA
蛋白名称
Integrin alpha-V
别名
ITGAV;MSK8;VNRA;Integrin alpha-V;Vitronectin receptor subunit alpha;CD antigen CD51
Organism-1
Human
基因ID-1
3685
SwissProt-1
P06756
Organism-2
Mouse
基因ID-2
16410
SwissProt-2
P43406
背景
integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion .
