Histone H4 (Acetyl Lys5) Rabbit mAb

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产品规格:
  • 100ul
货号:

FAB2621834

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商品描述
  • 靶点-Target

    Histone H4

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Acetyl

  • 修饰-Modification

    Lys5

  • MW(Calculated)

    11kD

  • MW(Observed)

    11kD

  • 推荐稀释比

    IHC 1:500-1:2000;WB 1:10000-1:50000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT1077R

  • 特异性

    Histone H4 (Acetyl Lys5) Monoclonal Antibody detects endogenous levels of Histone H4 protein only when acetylated at K5.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RGkGG

  • 基因名称

    HIST1H4A/HIST1H4B/HIST1H4C/HIST1H4D/HIST1H4E/HIST1H4F/HIST1H4H/HIST1H4I/HIST1H4J/HIST1H4K/HIST1H4L/HIST2H4A/HIST2H4B/HIST4H4

  • 蛋白名称

    Histone H4

  • 别名

    HIST1H4A;H4/A;H4FA;HIST1H4B;H4/I;H4FI;HIST1H4C;H4/G;H4FG;HIST1H4D;H4/B;H4FB;HIST1H4E;H4/J;H4FJ;HIST1H4F;H4/C;H4FC;HIST1H4H;H4/H;H4FH;HIST1H4I;H4/M;H4FM;HIST1H4J;H4/E;H4FE;HIST1H4K;H4/D;H4FD;HIST1H4L;H4/K;H4FK;H4K5AC

  • Organism-1

    Human

  • 基因ID-1

    121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370

  • SwissProt-1

    P62805

  • Organism-2

    Mouse

  • 基因ID-2

    100041230

  • SwissProt-2

    P62806

  • Organism-3

    Rat

  • 基因ID-3

    100360950

  • SwissProt-3

    P62804

  • 背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015],

  • 细胞定位

    Nucleus. Chromosome.