FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SRSF2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
25kD
MW(Observed)
35kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1053R
特异性
Endogenous
基因名称
SRSF2 SFRS2
蛋白名称
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Organism-1
Human
基因ID-1
6427
SwissProt-1
Q01130
Organism-2
Mouse
基因ID-2
20382
SwissProt-2
Q62093
Organism-3
Rat
基因ID-3
20382
SwissProt-3
Q6PDU1
背景
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]
细胞定位
Nucleus . Nucleus, nucleoplasm . Nucleus speckle . Phosphorylation by SRPK2 provokes its redistribution from the nuclear speckle to nucleoplasm.
