FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Bmi-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
37kD
MW(Observed)
43kD
推荐稀释比
IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1051R
特异性
Endogenous
基因名称
BMI1
蛋白名称
Polycomb complex protein BMI-1
别名
BMI1;PCGF4;RNF51;Polycomb complex protein BMI-1;Polycomb group RING finger protein 4;RING finger protein 51
Organism-1
Human
基因ID-1
648
SwissProt-1
P35226
Organism-2
Mouse
SwissProt-2
P25916
背景
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus . Cytoplasm .
