FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SERCA2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
115kD
MW(Observed)
140kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1034R
特异性
Endogenous
基因名称
ATP2A2
蛋白名称
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
别名
ATP2A2;ATP2B;Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;SERCA2;SR Ca;2+;-ATPase 2;Calcium pump 2;Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;Endoplasmic reticulum class 1/2 Ca;2+;ATPase
Organism-1
Human
基因ID-1
488
SwissProt-1
P16615
Organism-2
Mouse
基因ID-2
11938
SwissProt-2
O55143
Organism-3
Rat
基因ID-3
29693
SwissProt-3
P11507
背景
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein .
