- 产品信息
商品描述
靶点-Target
Histone H2A.Z
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
14kD
MW(Observed)
14kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;CHIP 1:50-1:100;Cut&Tag 1:50-1:100;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1032R
特异性
Endogenous
基因名称
H2AFZ H2AZ
蛋白名称
Histone H2A.Z (H2A/z)
别名
Histone H2A.Z;H2A/z;
Organism-1
Human
基因ID-1
3015
SwissProt-1
P0C0S5
Organism-2
Mouse
基因ID-2
51788
SwissProt-2
P0C0S6
Organism-3
Rat
基因ID-3
58940
SwissProt-3
P0C0S7
背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Chromosome.





