- 产品信息
商品描述
靶点-Target
GCN2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
187kD
MW(Observed)
187kD
推荐稀释比
IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0972R
特异性
Endogenous
基因名称
EIF2AK4
蛋白名称
Eukaryotic translation initiation factor 2-alpha kinase 4
别名
EIF2AK4;GCN2;KIAA1338;Eukaryotic translation initiation factor 2-alpha kinase 4;GCN2-like protein
Organism-1
Human
基因ID-1
440275
SwissProt-1
Q9P2K8
Organism-2
Mouse
基因ID-2
27103
SwissProt-2
Q9QZ05
背景
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014],
细胞定位
Cytoplasm .





