- 产品信息
商品描述
靶点-Target
MyD88
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
33kD
MW(Observed)
33kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0980R
特异性
Endogenous
基因名称
MyD88
蛋白名称
Myeloid differentiation primary response protein MyD88
别名
MYD88;Myeloid differentiation primary response protein MyD88
Organism-1
Human
基因ID-1
4615
SwissProt-1
Q99836
Organism-2
Mouse
基因ID-2
17874
SwissProt-2
P22366
Organism-3
Rat
基因ID-3
301059
SwissProt-3
Q6Y1S1
背景
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm . Nucleus .





