FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RSK3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
83kD
MW(Observed)
90kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0949R
特异性
Endogenous
基因名称
RPS6KA2 MAPKAPK1C RSK3
蛋白名称
RSK3 (Phospho Thr353)
别名
Ribosomal protein S6 kinase alpha-2;S6K-alpha-2;90 kDa ribosomal protein S6 kinase 2;p90-RSK 2;p90RSK2;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;Ribosomal S6 kinase 3;RSK-3;pp90RSK3;
Organism-1
Human
基因ID-1
6196
SwissProt-1
Q15349
Organism-2
Mouse
基因ID-2
20112
SwissProt-2
Q9WUT3
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.,
细胞定位
Nucleus . Cytoplasm .
