FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FPGS
反应性
Human,Mouse,Rat
应用
WB,FC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
65kDa
MW(Observed)
65kDa
推荐稀释比
WB 1:1000-1:5000;FC 1:100-1:500;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1133R
特异性
Endogenous
基因名称
FPGS
蛋白名称
Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)
Organism-1
Human
基因ID-1
2356
SwissProt-1
Q05932
Organism-2
Mouse
基因ID-2
14287
SwissProt-2
P48760
背景
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
细胞定位
SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion inner membrane {ECO:0000269|PubMed:16169100}. Mitochondrion matrix {ECO:0000269|PubMed:16169100, ECO:0000269|PubMed:8408020, ECO:0000269|PubMed:8662720}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:8662720}.
