- 产品信息
商品描述
靶点-Target
Glyt2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
88kDa
MW(Observed)
88kDa
推荐稀释比
WB 1:1000-1:5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1132R
特异性
Endogenous
基因名称
SLC6A5,GLYT2,NET1
蛋白名称
Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)
别名
GLYT2 NET1
Organism-1
Human
基因ID-1
9152
SwissProt-1
Q9Y345
Organism-2
Mouse
基因ID-2
104245
SwissProt-2
Q761V0
Organism-3
Rat
基因ID-3
171148
SwissProt-3
P58295
背景
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
细胞定位
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16751771, ECO:0000269|PubMed:31370103}; Multi-pass membrane protein {ECO:0000255}.





