Glyt2 (PT1132R) PT® Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

一键复制产品信息
产品规格:
  • 50μL
货号:

FAB2621762

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Glyt2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    88kDa

  • MW(Observed)

    88kDa

  • 推荐稀释比

    WB 1:1000-1:5000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1132R

  • 特异性

    Endogenous

  • 基因名称

    SLC6A5,GLYT2,NET1

  • 蛋白名称

    Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)

  • 别名

    GLYT2 NET1

  • Organism-1

    Human

  • 基因ID-1

    9152

  • SwissProt-1

    Q9Y345

  • Organism-2

    Mouse

  • 基因ID-2

    104245 

  • SwissProt-2

    Q761V0 

  • Organism-3

    Rat

  • 基因ID-3

    171148

  • SwissProt-3

    P58295

  • 背景

    This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

  • 细胞定位

    SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16751771, ECO:0000269|PubMed:31370103}; Multi-pass membrane protein {ECO:0000255}.