- 产品信息
商品描述
靶点-Target
BSND
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
35kDa
MW(Observed)
35kDa
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1122R
特异性
Endogenous
基因名称
BSND,BART
蛋白名称
Barttin
别名
BART
Organism-1
Human
基因ID-1
7809
SwissProt-1
Q8WZ55
Organism-2
Mouse
基因ID-2
140475
SwissProt-2
Q8VIM4
Organism-3
Rat
基因ID-3
192675
SwissProt-3
Q8R2H3
背景
This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. [provided by RefSeq, Jul 2008]
细胞定位
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000269|PubMed:18776122}; Multi-pass membrane protein {ECO:0000255}. Note=Mostly sorted at the basolateral membrane. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.





