BSND (PT1122R) PT® Rabbit mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621752

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商品描述
  • 靶点-Target

    BSND

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    35kDa

  • MW(Observed)

    35kDa

  • 推荐稀释比

    IHC 1:200-1:1000;WB 1:1000-1:5000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1122R

  • 特异性

    Endogenous

  • 基因名称

    BSND,BART

  • 蛋白名称

    Barttin

  • 别名

    BART

  • Organism-1

    Human

  • 基因ID-1

    7809

  • SwissProt-1

    Q8WZ55

  • Organism-2

    Mouse

  • 基因ID-2

    140475

  • SwissProt-2

    Q8VIM4

  • Organism-3

    Rat

  • 基因ID-3

    192675

  • SwissProt-3

    Q8R2H3

  • 背景

    This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. [provided by RefSeq, Jul 2008]

  • 细胞定位

    SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000269|PubMed:18776122}; Multi-pass membrane protein {ECO:0000255}. Note=Mostly sorted at the basolateral membrane. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.