NOP10 (PT1121R) PT® Rabbit mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621751

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商品描述
  • 靶点-Target

    NOP10

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    7kDa

  • MW(Observed)

    7kDa

  • 推荐稀释比

    IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1121R

  • 特异性

    Endogenous

  • 基因名称

    NOP10,NOLA3

  • 蛋白名称

    H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10)

  • 别名

    NOLA3

  • Organism-1

    Human

  • 基因ID-1

    55505

  • SwissProt-1

    Q9NPE3

  • Organism-2

    Mouse

  • 基因ID-2

    66181

  • SwissProt-2

    Q9CQS2

  • 背景

    This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008]

  • 细胞定位

    SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:11074001}. Nucleus, Cajal body {ECO:0000269|PubMed:11074001}. Note=Also localized to Cajal bodies (coiled bodies).