- 产品信息
商品描述
靶点-Target
ALKBH2
反应性
Human,Mouse,Rat
应用
WB,FC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
29kDa
MW(Observed)
29kDa
推荐稀释比
WB 1:1000-1:5000;FC 1:100-1:500;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1116R
特异性
Endogenous
基因名称
ALKBH2 ABH2
蛋白名称
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 (Alkylated DNA repair protein alkB homolog 2) (DNA oxidative demethylase ALKBH2) (Oxy DC1)
Organism-1
Human
基因ID-1
121642
SwissProt-1
Q6NS38
Organism-2
Mouse
SwissProt-2
Q6P6J4
背景
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008],
细胞定位
Nucleus . Nucleus, nucleolus . Nucleus, nucleoplasm . Relocates to the replication foci during S-phase. .





