OXGR1 (PT1104R) PT® Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621734

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商品描述
  • 靶点-Target

    OXGR1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    37kDa

  • MW(Observed)

    37kDa

  • 推荐稀释比

    WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1104R

  • 特异性

    Endogenous

  • 基因名称

    OXGR1 GPR80 GPR99 P2RY15 P2Y15

  • 蛋白名称

    2-oxoglutarate receptor 1 (Alpha-ketoglutarate receptor 1) (G-protein coupled receptor 80) (G-protein coupled receptor 99) (P2Y purinoceptor 15) (P2Y15) (P2Y-like GPCR) (P2Y-like nucleotide receptor)

  • Organism-1

    Human

  • 基因ID-1

    27199

  • SwissProt-1

    Q96P68

  • Organism-2

    Mouse

  • SwissProt-2

    Q6IYF8

  • Organism-3

    Rat

  • SwissProt-3

    Q6Y1R5

  • 背景

    This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],

  • 细胞定位

    Cell membrane; Multi-pass membrane protein.